Real-world comparison of health care utilization between duloxetine and pregabalin initiators with fibromyalgia

X Peng,1 P Sun,2 D Novick,1 J Andrews,1 S Sun2 1Eli Lilly and tapered-breast-plate Company, Indianapolis, IN, USA; 2Kailo Research Group, Indianapolis, IN, USA Objectives: To compare health care utilization of duloxetine initiators and pregabalin initiators among fibromyalgia patients in a real-world setting.Methods: A retrospective cohort study wa

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Efficient diagnosis of IDH-mutant gliomas: 1p/19qNET assesses 1p/19q codeletion status using weakly-supervised learning

Abstract Accurate identification of molecular alterations in gliomas Accessories is crucial for their diagnosis and treatment.Although, fluorescence in situ hybridization (FISH) allows for the observation of diverse and heterogeneous alterations, it is inherently time-consuming and challenging due to the limitations of the molecular method.Here, we

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Mutation in the two-component regulator BaeSR mediates cefiderocol resistance and enhances virulence in Acinetobacter baumannii

ABSTRACT Acinetobacter baumannii has become one of the most challenging pathogens in Used Goalie Set many countries with limited treatment options available.Cefiderocol, a novel siderophore-conjugated cephalosporin, shows potent in vitro activity against A.baumannii, including isolates resistant to carbapenems.To date, few reports on the mechanisms

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